This paper constructs an analytical framework that includes intelligent technology and GVC, verifying the impact of intelligent development on the upgrading of global value chains and its mechanism from both theoretical and empirical aspects. The research shows that the level of intelligence and the division status of the regional GVC has a significant positive impact. After considering the endogeneity and heterogeneity issues, the positive impact is robust; Also, the effect of intelligence on GVC rising is more pronounced in areas where factor endowments and policies are lacking advantages; Intelligence increases GVC by increasing the two channels of value added rate and technological sophistication. However, the existence of technology gaps, intelligent export value-added effect fails to be reflected in technology-intensive industries. Therefore, China’s breakthrough in the “low-end lock” of the global value chain must promote the deep integration of the Internet, big data, artificial intelligence, and the economy, and achieve the mid-to-high-end of GVC.